You can try to run MARNA on your local machine. I have written a preliminary
version which is executable on my machine and hopefully on your machine as well. I use a 2.8 GHz
Pentium IV machine, kernel version 2.6. OS: Suse Linux 9.2.
If you have a similar machine and if you have installed T-Coffee, the RNA Vienna Package and RNAshapes
then the chances are great that MARNA runs fully on your local machine.
Then test it with './marna.pl test.efasta'.
- Install tcoffee such that it can be run globally from any directory
- Install Vienna RNA package (RNAfold/RNAsubopt)
such that it can be run globally from any directory
- Download MARNA-100729.tar.gz.
- Unpack it with 'tar -xzf MARNA-100729.tar.gz'
- Change the unpacked source directory with 'cd MARNA'
- Check install notes and further information in file 'INSTALL.readme' (e.g. with 'less INSTALL.readme')
- Compile with 'make'
Reports are welcome !
If something seems to be wrong, then don't hesitate to write an email to :
rna[ @ ]informatik.uni-freiburg.de
Please cite :
Sven Siebert and Rolf Backofen,
"MARNA: multiple alignment and consensus structure prediction of RNAs based on sequence structure comparisons",
Bioinformatics 2005, Volume 21, Issue 16, 3352-3359
- 2010-07-29 : Martin Mann : source updated to compile with g++ 4.3.4
- 2006-02-24 : Sven Siebert : initial source package