@inproceedings{pudimat:2004:gcb, author = {Rainer Pudimat and E. G. Schukat-Talamazzini and Rolf Backofen}, title = { Feature Based Representation and Detection of Transcription Factor Binding Sites}, editor = {Robert Giegerich and Jens Stoye}, booktitle = GCB, publisher = {GI}, series = {LNI}, volume = 53, year = 2004, pages = {43-52}, user = {rpudimat}, abstract = { The prediction of transcription factor binding sites is an important problem, since it reveals information about the transcriptional regulation of genes. A commonly used representation of these sites are position specific weight matrices which show weak predictive power. We introduce a feature-based modelling approach, which is able to deal with various kind of biological properties of binding sites and models them via em Bayesian belief networks. The presented results imply higher model accuracy in contrast to the PSSM approach. }, keywords = {Bayesian networks, transcription factor binding sites, stochastic modelling, gene expression}, publists = {All and Rainer Pudimat and Rolf Backofen} }