@Article{Hiller:Huse:Szafranski:Wides_occur_alter:2004,
  author =	 {Hiller, Michael and Huse, Klaus and Szafranski, Karol and 
                  Jahn, Niels and Hampe, Jochen and Schreiber, Stefan and 
                  Backofen, Rolf and Platzer, Matthias},
  title =	 {{Widespread} occurrence of alternative splicing at {NAGNAG} 
                  acceptors contributes to proteome plasticity},
  journal =	 {Nat Genet},
  year =	 {2004},
  volume =	 {36},
  number =	 {12},
  pages =	 {1255-7},
  issn  =        {1061-4036},
  user =	 {hiller},
  annote =	 {bioinformatics},
  publists =	 {All and Michael Hiller and Rolf Backofen},
    pmid =	 {15516930},
  abstract =	 {Splice acceptors with the genomic NAGNAG motif may cause 
                  NAG insertion-deletions in transcripts, occur in 30% of 
                  human genes and are functional in at least 5% of human 
                  genes. We found five significant biases indicating that 
                  their distribution is nonrandom and that they are 
                  evolutionarily conserved and tissue-specific. Because of 
                  their subtle effects on mRNA and protein structures, these 
                  splice acceptors are often overlooked or underestimated, but 
                  they may have a great impact on biology and disease.}
}