@Article{Fallmann_Will_Engelhardt-Recen_advan_RNA-2017,
  author =	 {Fallmann, Jorg and Will, Sebastian and Engelhardt, Jan and 
                  Gruning, Bjorn and Backofen, Rolf and Stadler, Peter F.},
  title =	 {Recent advances in {RNA} folding},
  journal =	 {J Biotechnol},
  year =	 {2017},
  volume =	 {261},
  number =	 {},
  pages =	 {97-104},
  user =	 {backofen},
  pmid =	 {28690134},
  doi = 	 {10.1016/j.jbiotec.2017.07.007},
  issn = 	 {1873-4863},
  issn = 	 {0168-1656},
  abstract =	 {In the realm of nucleic acid structures, secondary 
                  structure forms a conceptually important intermediate level 
                  of description and explains the dominating part of the free 
                  energy of structure formation. Secondary structures are well 
                  conserved over evolutionary time-scales and for many classes 
                  of RNAs evolve slower than the underlying primary sequences. 
                  Given the close link between structure and function, 
                  secondary structure is routinely used as a basis to explain 
                  experimental findings. Recent technological advances, 
                  finally, have made it possible to assay secondary structure 
                  directly using high throughput methods. From a computational 
                  biology point of view, secondary structures have a special 
                  role because they can be computed efficiently using exact 
                  dynamic programming algorithms. In this contribution we 
                  provide a short overview of RNA folding algorithms, recent 
                  additions and variations and address methods to align, 
                  compare, and cluster RNA structures, followed by a tabular 
                  summary of the most important software suites in the fields.}
}