@Article{Fallmann_Videm_Bagnacani-The_RNA_workb-NAR2019, author = {Fallmann, J\"org and Videm, Pavankumar and Bagnacani, Andrea and Batut, Berenice and Doyle, Maria A. and Klingstrom, Tomas and Eggenhofer, Florian and Stadler, Peter F. and Backofen, Rolf and Gr\"uning, Bjorn}, title = {The {RNA} workbench 2.0: next generation {RNA} data analysis}, journal = NAR, year = {2019}, volume = {47}, number = {W1}, pages = {W511-W515}, user = {egg}, pmid = {31073612}, doi = {10.1093/nar/gkz353}, issn = {1362-4962}, issn = {0305-1048}, abstract = {RNA has become one of the major research topics in molecular biology. As a central player in key processes regulating gene expression, RNA is in the focus of many efforts to decipher the pathways that govern the transition of genetic information to a fully functional cell. As more and more researchers join this endeavour, there is a rapidly growing demand for comprehensive collections of tools that cover the diverse layers of RNA-related research. However, increasing amounts of data, from diverse types of experiments, addressing different aspects of biological questions need to be consolidated and integrated into a single framework. Only then is it possible to connect findings from e.g. RNA-Seq experiments and methods for e.g. target predictions. To address these needs, we present the RNA Workbench 2.0 , an updated online resource for RNA related analysis. With the RNA Workbench we created a comprehensive set of analysis tools and workflows that enables researchers to analyze their data without the need for sophisticated command-line skills. This update takes the established framework to the next level, providing not only a containerized infrastructure for analysis, but also a ready-to-use platform for hands-on training, analysis, data exploration, and visualization. The new framework is available at https://rna.usegalaxy.eu , and login is free and open to all users. The containerized version can be found at https://github.com/bgruening/galaxy-rna-workbench.} }