Bioinformatics
Institute of Computer Science
University Freiburg
de

Proseminar : Introduction to Bioinformatics

Lecturer

Mehmet Tekman, Milad Miladi, Van Dinh Tran

Dates

Organisation

Topics

Group Talks

GroupChaptersAssigned toOverlapping Topics
1 11, 23 Ehsainieh, and Reifsteck
  • Gene structure (eukaryotes, prokaryotes)
  • Introns/exons, open reading frame, coding DNA sequence
  • Cis/trans-acting
2 01, 19, 22 Köhl, Legeland, and Biermann
  • Central dogma of molecular biology
  • RNA types (e.g. mRNA, rRNA, tRNA, ncRNA, siRNA, miRNA)
  • RNA-RNA interactions and hybrids
  • Thermodynamics of RNA structures (MFE, free energy structure)
3 02, 03 Türk, and Karg
  • Local sequence alignment
  • Global and multiple sequence alignment
  • Phylogeny (basics)
4 04, 13, 25 Kreutzarek, Engelhardt, and Borukhson
  • Gene regulation
  • Post-transcriptional modifications
  • Post-translational modifications
  • Gene splicing and silencing (RNAi)
5 08, 09 Rodko, and Gutmann
  • RNA sequencing (basics, overview)
  • Biological sample preparation
  • Bioinformatic analysis